Items tagged with Vaccines
TB vaccines can vary greatly, study finds. But does that mean some are less protective? (post)
It all started with a bit of bacteria swiped from the udder of a tuberculous French cow. Initially, it was just another livestock sample, a speck of virulence lounging in a Paris lab. But then it began to change. Two scientists had brought some of it to Lille, near the Belgian border, and had fed it a concoction of potato, glycerin, and ox bile. The bugs liked this witches’ brew, and multiplied, and multiplied again.
GSK licenses TB vaccine candidate to the Bill & Melinda Gates Medical Research Institute for continued development (post)
-- The M72/AS01E tuberculosis vaccine candidate demonstrated in a phase IIb trial the potential to reduce active pulmonary TB by half in adults with latent TB infection.[1]
-- Developing a new vaccine against TB is a global health priority to accelerate progress toward ending the TB epidemic[2] and one of the United Nations Sustainable Development Goals
-- The licensing agreement is a significant step forward to continue the development of the vaccine candidate for low-income countries with high TB burdens.
Webinar: What’s New—and Next—for TB Vaccines (post)
Treatment Action Group (TAG) and AVAC will host a webinar on 6 February 2020 featuring an update on recent vaccine results and possible next steps with M72/AS01E, one of several new TB vaccine candidates.
The status of TB vaccine development (post)
TB represents the leading global cause of death from an infectious agent. Controlling the TB epidemic thus represents an urgent global public health priority. Epidemiological modelling suggests that, although drug treatments for TB continue to improve, WHO timelines to control the spread of the disease require a new vaccine capable of preventing TB, particularly in adolescents and adults.
Can a century-old TB vaccine steel the immune system against the new coronavirus? (post)
Researchers in four countries will soon start a clinical trial of an unorthodox approach to the new coronavirus. They will test whether a century-old vaccine against tuberculosis (TB), a bacterial disease, can rev up the human immune system in a broad way, allowing it to better fight the virus that causes coronavirus disease 2019 and, perhaps, prevent infection with it altogether. The studies will be done in physicians and nurses, who are at higher risk of becoming infected with the respiratory disease than the general population, and in the elderly, who are at higher risk of serious illness if they become infected.
An old TB vaccine finds new life in coronavirus trials (post)
Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.
Researchers unlock BCG vaccine puzzle in findings that could save millions of newborns (post)
Telethon Kids Institute researchers working with a global team have identified the mechanism behind one of science’s most enduring mysteries: what makes the 100-year-old tuberculosis (TB) vaccine, BCG, so effective at preventing newborn deaths from diseases other than TB.
TB vaccine strengthens immune system (post)
Study by the Universities of Bonn and Nijmegen explains how BCG vaccination reduces susceptibility to infections
Sydney researchers test TB vaccine combination for COVID-19 (post)
Sydney researchers are taking an innovative approach to designing potential COVID-19 vaccines - using a tuberculosis vaccine to deliver components of the SARS-CoV-2 virus. Early results from pre-clinical testing in mice are promising.
Preliminary study suggests TB vaccine may be limiting COVID-19 deaths (post)
One of the emerging questions about the coronavirus that scientists are working to understand is why developing countries are showing markedly lower rates of mortality in COVID-19 cases than expected.
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