Items tagged with Treatment

South Africa: New TB drug gets ‘fast-track status’ (post)

Cape Town - Patients with multidrug-resistant (MDR) tuberculosis could soon have access to a promising new drug – Bedaquiline – as the Medicines Control Council (MCC) is “fast-tracking” its authorisation processes to have the drug licensed.

Patient support interventions to improve adherence to drug resistant tuberculosis (DR-TB) treatment - a counseling toolkit (post)

25 June 2014 - Khayelitsha, South Africa - Khayelitsha, a township in the Western Cape, South Africa, is home to approximately 500,000 residents and has some of the highest rates of HIV and tuberculosis globally. In response to the growing burden of drug-resistant tuberculosis (DR-TB) in Khayelitsha, Medecins Sans Frontieres (MSF), in collaboration with the City of Cape Town Health and the Provincial Government of the Western Cape, began piloting a decentralized model of care for DR-TB in 2007. The patient-centered, community-based model was thereafter implemented in 10 primary health care clinics (PHC) within the sub-district, and is now managed in its entirety by the local Department of Health. In 2011, various aspects of this decentralized model were adopted and implemented across other sub-districts in Cape Town as well as other provinces in South Africa.

TB drug resistance signifies failure (post)

LONDON, 9 July 2014 (IRIN) - Tuberculosis control programmes are among the oldest public health campaigns (dating back 125 years) but are not nearly as successful as they should be. Despite effective drugs having been available for over 50 years, TB still kills a million people a year, making it the world's single deadliest infectious disease after AIDS.

India: Study finds doctors also adding to burden of drug-resistant TB cases (post)

PUNE: It is not just the patients who default on treatment, but also private doctors who are to blame for the rise in drug-resistant cases of tuberculosis.

Novel TB regimen could reduce treatment duration (post)

A novel TB drug regimen could treat drug-sensitive and some forms of drug-resistant TB far more quickly than current standard TB therapy, according to findings from a phase IIb trial were presented today at the 20th International AIDS Conference (AIDS 2104) in Melbourne, Australia.

New TB treatment drug gets mixed reaction (post)

The University of Cape Town's (UCT) head of Pulmonology division, Professor Keertan Dheda, says he is less optimistic about the cocktail of drugs for drug-resistance TB.

Treating MDR-TB increased risk of acquired resistance to second-line drugs (post)

The treatment of multidrug-resistant tuberculosis significantly increases the risk of acquired resistance to second-line drugs and upgrading the condition to extensively drug-resistant tuberculosis, according to data from a new study.

Use of drug susceptibility testing to select therapy improves treatment outcomes in patients with MDR- and XDR-TB (post)

New research published in the online edition of Clinical Infectious Diseases supports World Health Organization (WHO) recommendations for the use of drug susceptibility testing to select drugs for the treatment of drug-resistant tuberculosis. Drug susceptibility testing for ethambutol, pyrazinamide and second-line anti-tuberculosis (TB) treatment was shown to provide clinically useful information for the selection of treatment regimens for multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB). The chances of treatment success were increased between 1.7 and 4.6-fold when susceptibility testing showed that the use of an individual agent was appropriate.

Rapid MDR-TB test improved clinical outcomes (post)

A rapid molecular diagnostic test significantly reduced the time to treatment initiation in patients with multidrug-resistant tuberculosis, new data suggest.

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