Items tagged with HIV coinfection
Steroids raise cancer risk in TB-associated HIV (post)
BARCELONA, Spain – Tuesday 2 September 2014: The addition of steroids to tuberculosis (TB) therapy can offer anti-inflammatory benefit to patients with tuberculous pericarditis, a rare cardiac manifestation of TB.
Pre-ART profile differs for mortality and TB-IRIS in people starting ART (post)
Most immune-related cytokine levels before antiretroviral therapy (ART) began were higher in Botswana patients who died soon after starting ART than in people who did not die [1]. In contrast, pre-ART cytokine levels were lower in people with TB immune reconstitution inflammatory syndrome (IRIS) after starting ART than in the control group of survivors without TB-IRIS.
IRIS and risk of early death among HIV+ people with tuberculosis (post)
People coinfected with HIV and tuberculosis (TB) who go onto develop immune reconstitution inflammatory syndrome (IRIS) while on antiretroviral therapy (ART) have a pre-ART immunological profile that is easily distinguishable from those who are at risk of early mortality despite being treated for both HIV and TB, according to a presentation at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy this month in Washington, DC.
Adherence to ART and XDR-TB therapy in Kwa-Zulu Natal province (post)
Adherence to antiretroviral therapy (ART) approached 90% in a 104-person prospective study in KwaZulu-Natal province, South Africa. Adherence to multiple medications for extensively drug-resistant tuberculosis (XDR-TB) was 20% lower.
Nevirapine or efavirenz for tuberculosis and HIV coinfected patients: exposure and virological failure relationship (post)
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In Rio group over 10% diagnosed with HIV also have tuberculosis (post)
Slightly more than 10% in a Rio de Janeiro cohort with newly diagnosed HIV infection already had tuberculosis, according to results of a 4500-person study. Although antiretroviral therapy (ART) started faster in the people with than without TB, those with TB had almost a 75% higher early death risk.
6 ways to fix South Africa’s HIV response (post)
South African sex workers may have one of the world’s highest HIV prevalence rates and addressing this is just one of six ways South African National AIDS Council (SANAC) CEO Dr Fareed Abdullah says the country can fix its HIV response.
Newly identified marker helps predict tuberculosis complications in HIV patients (post)
An NIAID study suggests that the increased frequency of an immune cell called CD14++CD16- monocyte is a strong indicator that a patient with HIV and tuberculosis (TB) may develop complications from anti-HIV drugs. For unclear reasons, a subset of people with both HIV and TB experience worsening of their TB symptoms after starting antiretroviral therapy (ART) to treat HIV. The study, which appears in the October 2, 2014, issue of PLOS Pathogens, offers a better understanding of why this may occur.
High uptake of systematic HIV counseling and testing and TB symptom screening at a primary care clinic in South Africa (post)
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Isoniazid significantly reduced TB incidence in HIV patients receiving HAART (post)
PHILADELPHIA, PA—The use of isoniazid as preventive therapy among HIV-infected patients receiving highly active antiretroviral therapy (HAART) is associated with significantly lower tuberculosis incidence, reported Bethel Shiferaw, MD, MPH, from Nassau University Medical Center, East Meadow, at IDWeek 2014.
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