Estie Mermelstein

Frequency of adverse events in patients with multidrug-resistant TB

Among patients with multidrug-resistant tuberculosis (MDR-TB), adverse events related to treatment with linezolid and injectable drugs were found to be more common compared with those related to bedaquiline and delamanid, according to a multicenter, prospective observational study published in Clinical Infectious Diseases.

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Optimal dosing of rifampicin/isoniazid/pyrazinamide in children with TB

Treatment with an updated fixed-dose combination (FDC) of rifampicin/isoniazid/ pyrazinamide may decrease the risk for insufficient exposure to rifampicin among children with tuberculosis (TB) infection, according to results of a prospective study published in Clinical Infectious Diseases.

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Hyperglycemia unresolved in 50% of TB patients posttreatment

More than half of tuberculosis (TB) patients with newly diagnosed hyperglycemia at TB treatment initiation have unresolved hyperglycemia at the end of their follow-up period, according to data from a meta-analysis published in BMC Infectious Diseases. Findings suggest a need for diabetes mellitus (DM) screening at more frequent intervals during TB treatment.

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