World Health Organization

Framework for the evaluation of new tests for tuberculosis infection

29 July 2020 | GENEVA - The World Health Organization (WHO) and the Stop TB Partnership’s New Diagnostics Working Group (NDWG) launched today a framework for the evaluation of new tests for tuberculosis infection. The document provides details on study design, populations, reference standards, sample size calculation and data analysis to guide the future development of these tests.

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WHO public call for data on the management of TB in children and adolescents

24 July 2020, Geneva | WHO is initiating the development of updated guidelines on the management of TB in children and adolescents. The second edition of the Guidance for national tuberculosis programmes on the management of tuberculosis in children was published in 2014. Since then, several recommendations included in this guidance have been updated as part of other WHO guidelines, including recommendations on TB preventive treatment, treatment of drug-resistant TB, rapid diagnostics. An update to the TB screening guidelines is currently in process.

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Call for expressions of interest: Systematic reviews on dose optimization of the first-line TB medicines

22 July 2020, Geneva | The World Health Organization (WHO) Global Tuberculosis Programme has initiated a process for the collection and assessment of evidence on whether the dosing of rifampicin, isoniazid, ethambutol and pyrazinamide requires further optimization to safely improve treatment success and reduce unfavourable treatment outcomes in TB patients on first-line treatment regimens.

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Webinar: From Policy to Practice: Rolling out new WHO guidelines on rapid diagnostics and drug-resistant TB treatment

The World Health Organization (WHO) will host a webinar on 9 July 2020 to provide key updates on recently released new WHO guidance on rapid diagnostics and drug-resistant TB treatment.

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Introductory meeting of WHO’s Strategic and Technical Advisory Group for TB

An introductory meeting of the World Health Organization (WHO) Strategic and Technical Advisory Group for Tuberculosis (STAG-TB) was held on 24-25 June 2020. The purpose of the meeting was to orient new STAG-TB members on their roles, the work of WHO and its Global TB Program and to overview the draft 2020 progress report of the UN Secretary General on TB.

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WHO urges countries to expand access to rapid molecular tests for the detection of TB and drug-resistant TB

WHO releases updated guidelines for TB diagnosis, recommending rapid molecular tests as initial tests for TB detection.

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Public call for data on diagnostic accuracy of nucleic acid amplification tests to detect TB and DR-TB

18 June 2020, Geneva | Nucleic acid amplification tests (NAAT) are promising technologies for the rapid and accurate detection of TB and resistance to selected anti-TB agents. In December 2020, the World Health Organization (WHO) will convene a Guidelines Development Group (GDG) meeting to update its diagnostic guidelines on the use of NAATs to detect TB and resistance to selected anti-TB agents. Ahead of this meeting, WHO will commission reviews of relevant evidence on diagnostic accuracy for several NAAT assays.

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Update of the WHO guidance on screening for active TB

The World Health Organization (WHO) is convening a Guideline Development Group (GDG) to advise on updates needed to its recommendations on the systematic screening for tuberculosis (TB).

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WHO urges countries to enable access to fully-oral drug-resistant TB treatment regimens

WHO releases updated guidelines for the treatment of drug-resistant TB.

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WHO: Promoting research on the interlinkages between COVID-19 and TB

05 June 2020 | Geneva - The World Health Organization (WHO) Global TB Programme is pleased to share a compendium of key resources to facilitate knowledge sharing and promote research on the interlinkages between tuberculosis (TB) and COVID-19. Given similar disease presentation between TB and COVID-19, and the adverse impact of this pandemic on TB services and health outcomes, knowledge sharing is important for a timely response to the dual threat of COVID-19 and TB.

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