Latest TB research publications

Peripheral inflammatory response in human tuberculosis treatment is predicted by a combination of pathogen sterilization and microbiome dysbiosis

Matthew F Wipperman, Shakti K Bhattarai, Charles Kyriakos Vorkas, Ying Taur, Laurent Mathurin, Katherine McAulay, Stalz Charles Vilbrun, Daphie Jean Francois, James Bean, Kathleen F Walsh, Carl Nathan, Daniel W Fitzgerald, Vanni Bucci, Michael S Glickman

2020-03-13  //  MEDRXIV  //  Research Article

Extract from used Xpert MTB/RIF Ultra cartridges is useful for accurate second-line drug-resistant tuberculosis diagnosis with minimal rpoB -amplicon cross-contamination risk

Rouxjeane Venter, Stephanie Minnies, Brigitta Derendinger, Happy Tshivhula, Margaretha de Vos, Tania Dolby, Ashley Ruiters, Robin M. Warren & Grant Theron

2020-03-13  //  SCIENTIFIC REPORTS  //  Research Article

Novel Approach for Transdermal Delivery of Rifampicin to Induce Synerg

Hussain A, Altamimi MA, Alshehri S, Imam SS, Shakeel F, Singh SK

2020-03-13  //  IJN  //  Research Article

Arabinosyltransferase C enzyme of Mycobacterium tuberculosis, a potential drug target: An insight from molecular docking study

Nisha Das Pradip Kumar Jena Sukanta Kumar Pradhan

2020-03-13  //  HELIYON  //  Research Article

Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections

Estefanía Abascal, Marta Herranz, Fermín Acosta, Juan Agapito, Andrea M. Cabibbe, Johana Monteserin, María Jesús Ruiz Serrano, Paloma Gijón, Francisco Fernández-González, Nuria Lozano, Álvaro Chiner-Oms, Tatiana Cáceres, Pilar Gómez Pintado, Enrique Acín, Eddy Valencia, Patricia Muñoz, Iñaki Comas, Daniela M. Cirillo, Viviana Ritacco, Eduardo Gotuzzo & Darío García de Viedma

2020-03-13  //  SCIENTIFIC REPORTS  //  Research Article

Childhood tuberculosis treatment outcome and its association with HIV co-infection in Ethiopia: a systematic review and meta-analysis

Getaneh Mulualem Belay & Chalachew Adugna Wubneh

2020-03-13  //  TROPICAL MEDICINE AND HEALTH  //  Research Article

Does time to loss to follow-up differ among adult tuberculosis patients initiated on tuberculosis treatment and care between general hospital and health centers? A retrospective cohort study

Tamrat Shaweno, Masrie Getnet & Chaltu Fikru

2020-03-13  //  TROPICAL MEDICINE AND HEALTH  //  Research Article

Effect of the Xpert MTB/RIF on the detection of pulmonary tuberculosis cases and rifampicin resistance in Shanghai, China

Zheyuan Wu, Zulma Vanessa Rueda, Tao Li, Zurong Zhang, Yuan Jiang, Wei Sha, Fangyou Yu, Jing Chen, Qichao Pan, Xin Shen & Zheng’an Yuan

2020-03-13  //  BMC INFECTIOUS DISEASES  //  Research Article

Genome-wide identification of the context-dependent sRNA expression in Mycobacterium tuberculosis

Vimla Kany G. Ami, Rami Balasubramanian & Shubhada R. Hegde

2020-03-13  //  BMC GENOMICS  //  Research Article

A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic

Marisa Klopper, Tim Hermanus Heupink, Grant Hill-Cawthorne, Elizabeth Maria Streicher, Anzaan Dippenaar, Margaretha de Vos, Abdallah Musa Abdallah, Jason Limberis, Matthias Merker, Scott Burns, Stefan Niemann, Keertan Dheda, James Posey, Arnab Pain & Robin Mark Warren

2020-03-13  //  BMC MEDICINE  //  Research Article

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis

Lei Zhang, R. Curtis Hendrickson, Virginia Meikle, Elliot J. Lefkowitz, Thomas R. Ioerger, Michael Niederweis

2020-02-18  //  PLOS PATHOGENS  //  Research Article

TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis

Ainhoa Arbués, Dominique Brees, Salah-Dine Chibout, Todd Fox, Michael Kammüller, Damien Portevin

2020-02-18  //  PLOS PATHOGENS  //  Research Article

Monocytes from neonates and adults have a similar capacity to adapt their cytokine production after previous exposure to BCG and β-glucan

Rhoda Namakula, L. Charlotte J. de Bree, Tor Henrik A. Tvedt, Mihai G. Netea, Stephen Cose, Kurt Hanevik

2020-02-21  //  PLOS ONE  //  Research Article

Computational study of parameter sensitivity in DevR regulated gene expression

Jagannath Das, Tarunendu Mapder, Sudip Chattopadhyay, Suman K. Banik

2020-02-13  //  PLOS ONE  //  Research Article

National TB program shortages as potential factor for poor-quality TB care cascade: Healthcare workers’ perspective from Beira, Mozambique

Miguelhete Lisboa, Inês Fronteira, Paul H. Mason, Maria do Rosário O. Martins

2020-02-14  //  PLOS ONE  //  Research Article

A model-based investigation into urban-rural disparities in tuberculosis treatment outcomes under the Revised National Tuberculosis Control Programme in India

Himanshu Singh, Varun Ramamohan

2020-02-14  //  PLOS ONE  //  Research Article

Low enrollment and high treatment success in children with drug-resistant tuberculosis in Ethiopia: A ten years national retrospective cohort study

Habteyes Hailu Tola, Mohammad Ali Mansournia, Mehdi Yaseri, Ephrem Tesfaye, Zemedu Mahamed, Million Molla Sisay, Kourosh Holakouie-Naieni

2020-02-26  //  PLOS ONE  //  Research Article

Situating trade-offs: Stakeholder perspectives on overtreatment versus missed diagnosis in transition to Xpert MTB/RIF Ultra in Kenya and Swaziland

Muthoni Mwaura, Kekeletso Kao, Jesse Wambugu, Andre Trollip, Welile Sikhondze, Eunice Omesa, Sindi Dlamini, Nompumelelo Mzizi, Muyalo Dlamini, Busizwe Sibandze, Brian Dlamini, Heidi Albert, Wybo Dondorp, Nora Engel

2020-02-19  //  PLOS ONE  //  Research Article

Correction: Social, demographic, health care and co-morbidity predictors of tuberculosis mortality in Amazonas, Brazil: a multiple cause of death approach

Abby Hilling

2020-03-13  //  PLOS ONE  //  Research Article

Advances in clinical trial design: Weaving tomorrow’s TB treatments

Christian Lienhardt, Andrew Nunn, Richard Chaisson, Andrew A. Vernon, Matteo Zignol, Payam Nahid, Eric Delaporte, Tereza Kasaeva

2020-02-27  //  PLOS MEDICINE  //  Commentary