University of Southampton

Scientists close in on TB blood test which could detect millions of silent spreaders

Scientists have taken a major step towards developing a blood test that could identify millions of people who spread tuberculosis unknowingly.

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New studies identify how TB destroy the lungs and how to protect them

Two new studies have cast unprecedented light on disease processes in tuberculosis, identifying key genetic changes that cause damage in the lungs and a drug treatment that could speed up recovery.

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Innovative collaboration leads to new insights into TB immune response

New research using human lung samples and three-dimensional bioengineering techniques to replicate the lung environment has revealed the important role of a subset of immune cells in the lung in fighting tuberculosis (TB). The cells, called T Helper 17 cells, or Th17, have been found to be important in animal models of TB, but are rarely detected in the blood of humans and so their importance in human disease has not been clear until now.

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Research identifies how new cancer treatments can activate tuberculosis infection

Researchers at the University of Southampton have identified how new checkpoint inhibitor treatments for cancer can activate tuberculosis in some patients.

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Study opens new avenue in quest to develop TB vaccine

A team of scientists led by the University of Southampton has taken an important step forward in research efforts that could one day lead to an effective vaccine against the world’s deadliest infectious disease.

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Researchers use tiny 3D spheres to combat TB

Researchers at the University of Southampton have developed a new 3D system to study human infection in the laboratory.

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TB tricks the body’s immune system to allow it to spread

Tuberculosis (TB) tricks the immune system into attacking the body’s lung tissue so the bacteria are allowed to spread to other people, new research from the University of Southampton suggests.

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New study to improve tuberculosis treatments

The University of Southampton has been awarded $1.4 million (approximately £833,260) to develop new treatments to fight tuberculosis.

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New hope for improved TB treatments

Researchers at the University of Southampton have identified new markers of tuberculosis (TB) that may help in the development of new diagnostic tests and treatments.

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