History of tuberculosis increases risk for cardiovascular conditions, including ischemic heart disease and myocardial infarction.

Patients with diabetes mellitus (DM) and tuberculosis (TB) had a significantly higher incidence of low rifampicin plasma levels 2 hours after the anti-tubercular drug was administered, compared with patients with TB who did not have DM, according to results of a systematic review and meta-analysis recently published in the journal Therapies.

In patients with tuberculosis (TB), a host 22-gene RNA-based model has been identified that may be predictive of individual treatment durations with antimicrobial therapy, potentially leading to a substantially shorter treatment durations for many patients. This was among the results of an analysis recently published in the European Respiratory Journal.

A short, 9-month regimen of normal-dose moxifloxacin maintained good effectiveness up to 24 months after the cessation of therapy in patients with rifampicin-resistant tuberculosis (RR-TB), according to the results of an observational cohort study published in EClinicalMedicine.

Treatment for latent tuberculosis infection (LTBI) among patients between age 65 and 78 years has been shown to be relatively well tolerated, with completion rates decreasing according to age.

DALLAS — Positive results with respect to the presence of latent tuberculosis infection (LTBI) in patients with renal failure were more consistent with the use of QuantiFERON-TB Gold Plus (QFT-G plus) testing compared with the use of QuantiFERON-TB Gold In-Tube (QFT-GIT) testing.