Treatment of latent tuberculosis infection: A network meta-analysis

In many countries with a low incidence of tuberculosis (TB), many new cases emerge as a result of reactivation of latent TB infection (LTBI), which is often acquired in high-incidence areas or from recent exposure in occasional outbreaks. Therefore, such countries have had a renewed interest in LTBI screening and treatment, generally for groups at particularly high risk for reactivation, such as contacts of patients with pulmonary TB, persons who are immunocompromised, and migrants from high-incidence areas.