Latest TB research publications

VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response

Sakshi Agarwal, Arun Sharma, Rania Bouzeyen, Amar Deep, Harsh Sharma, Kiran K. Mangalaparthi, Keshava K. Datta, Saqib Kidwai, Harsha Gowda, Raghavan Varadarajan, Ravi Datta Sharma, Krishan Gopal Thakur and Ramandeep Singh

2020-06-16 // SCIENCE ADVANCES // Research Article

EDITOR'S PICK: Modelling the dynamics of tuberculosis lesions in a virtual lung: Role of the bronchial tree in endogenous reinfection

Martí Català, Jordi Bechini, Montserrat Tenesa, Ricardo Pérez, Mariano Moya, Cristina Vilaplana, Joaquim Valls, Sergio Alonso, Daniel López, Pere-Joan Cardona, Clara Prats

2020-05-20 // PLOS COMPUTATIONAL BIOLOGY // Research Article

Clofazimine enhances the efficacy of BCG revaccination via stem cell-like memory T cells

Shaheer Ahmad, Debapriya Bhattacharya, Neeta Gupta, Varsha Rawat, Sultan Tousif, Luc Van Kaer, Gobardhan Das

2020-05-21 // PLOS PATHOGENS // Research Article

The perceived impact of isoniazid resistance on outcome of first-line rifampicin-throughout regimens is largely due to missed rifampicin resistance

Armand Van Deun, Tom Decroo, Aung Kya Jai Maug, Mohamed Anwar Hossain, Murid Gumusboga, Wim Mulders, Nimer Ortuño-Gutiérrez, Lutgarde Lynen, Bouke C. de Jong, Hans L. Rieder

2020-05-18 // PLOS ONE // Research Article

Role of CD4/CD8 ratio on the incidence of tuberculosis in HIV-infected patients on antiretroviral therapy followed up for more than a decade

Dawit Wolday, Yazezew Kebede, Dorsisa Legesse, Dawd S. Siraj, Joseph A. McBride, Mitchell J. Kirsch, Robert Striker

2020-05-22 // PLOS ONE // Research Article

The social implications of participant choice on adherence to Isonaizid Preventive Therapy (IPT): A follow-up study to high completion rates in Eswatini

S. W. Grande, L. V. Adams, T. S. B. Maseko, E. A. Talbot, D. deGijsel, J. Mikal, Z. Z. Simelane, A. Achili, M. Mkhontfo, S. M. Haumba

2020-05-29 // PLOS ONE // Research Article

Nutritional assessment among adult patients with suspected or confirmed active tuberculosis disease in rural India

Elaine A. Yu, Julia L. Finkelstein, Patsy M. Brannon, Wesley Bonam, David G. Russell, Marshall J. Glesby, Saurabh Mehta

2020-05-22 // PLOS ONE // Research Article

Reconsidering Mycobacterium bovis as a proxy for zoonotic tuberculosis: a molecular epidemiological surveillance study

Shannon C Duffy, BSc Sreenidhi Srinivasan, PhD Megan A Schilling, PhD Tod Stuber, BSc Sarah N Danchuk, BSc Prof Joy S Michael, MD Manigandan Venkatesan, MSc Nitish Bansal, PhD Prof Sushila Maan, PhD Naresh Jindal, PhD Deepika Chaudhary, PhD Premanshu Dandapat, PhD Robab Katani, PhD Shubhada Chothe, PhD Maroudam Veerasami, PhD Suelee Robbe-Austerman, PhD Nicholas Juleff, PhD Prof Vivek Kapur, PhD Prof Marcel A Behr, MD

2020-06-16 // THE LANCET MICROBE // Research Article

Mycobacteria inhibit neutrophil recruitment to avoid neutrophil-assisted killing by macrophages

Sergio Candel, Lalita Ramakrishnan

2020-06-16 // BIORXIV // Research Article

Mycobacterium tuberculosis clinical isolates carry mutational signatures of host immune environments

Qingyun Liu, Jianhao Wei, Yawei Li, Mei Wang, Jun Su, Yonghui Lu, Mariana G. López, Xueqin Qian, Zhaoqin Zhu, Haiying Wang, Mingyun Gan, Qi Jiang, Yun-Xin Fu, Howard E. Takif, Iñaki Comas, Feng Li, Xuemei Lu, Sarah M. Fortune, and Qian Gao

2020-06-16 // SCIENCE ADVANCES // Research Article

Human T-cell leukemia virus type 1 may invalidate T-SPOT.TB assay results in rheumatoid arthritis patients: A retrospective case-control observational study

Kunihiko Umekita, Yayoi Hashiba, Kosho Iwao, Chihiro Iwao, Masatoshi Kimura, Yumi Kariya, Kazuyoshi Kubo, Shunichi Miyauchi, Risa Kudou, Yuki Rikitake, Katoko Takajo, Takeshi Kawaguchi, Motohiro Matsuda, Ichiro Takajo, Eisuke Inoue, Toshihiko Hidaka, Akihiko Okayama

2020-05-27 // PLOS ONE // Research Article

Designing an optimized diagnostic network to improve access to TB diagnosis and treatment in Lesotho

Heidi Albert, Ryan Purcell, Ying Ying Wang, Kekeletso Kao, Mathabo Mareka, Zachary Katz, Bridget Llang Maama, Tsietso Mots'oane

2020-06-03 // PLOS ONE // Research Article

Environmental DNA: A promising factor for tuberculosis risk assessment in multi-host settings

Jordi Martínez-Guijosa, Beatriz Romero, José Antonio Infantes-Lorenzo, Elena Díez, Mariana Boadella, Ana Balseiro, Miguel Veiga, David Navarro, Inmaculada Moreno, Javier Ferreres, Mercedes Domínguez, Cesar Fernández, Lucas Domínguez, Christian Gortázar

2020-05-29 // PLOS ONE // Research Article

Exploration of barriers and facilitators to household contact tracing of index tuberculosis cases in Anlemo district, Hadiya zone, Southern Ethiopia: Qualitative study

Legesse Tesfaye, Yohannes Kebede Lemu, Kasahun Girma Tareke, Mulugeta Chaka, Garumma Tolu Feyissa

2020-05-22 // PLOS ONE // Research Article

Altered systemic levels of acute phase proteins in tuberculous lymphadenitis and modulation after treatment

Gokul Raj Kathamuthu, Kadar Moideen, Nathella Pavan Kumar, Rathinam Sridhar, Dhanaraj Baskaran, Subash Babu

2020-05-29 // PLOS ONE // Research Article

Characteristics and predictors for tuberculosis related mortality in Denmark from 2009 through 2014: A retrospective cohort study

Inge K. Holden, Troels Lillebaek, Peter H. Andersen, Christian Wejse, Isik S. Johansen

2020-06-04 // PLOS ONE // Research Article

Evaluation of multi-antigen serological screening for active tuberculosis among people living with HIV

Devan Jaganath, Jayant Rajan, Christina Yoon, Resmi Ravindran, Alfred Andama, Lucy Asege, Sandra Z. Mwebe, Jane Katende, Martha Nakaye, Fred C. Semitala, Imran H. Khan, Adithya Cattamanchi

2020-06-04 // PLOS ONE // Research Article

Host cytosolic RNA sensing pathway promotes T Lymphocyte-mediated mycobacterial killing in macrophages

Yong Cheng, Nicholas J. Kiene, Alexandra Tatarian, Emily F. Eix, Jeffrey S. Schorey

2020-05-28 // PLOS PATHOGENS // Research Article

Prevalence of latent tuberculosis infection and associated risk factors in prison in East Wollega Zone of western Ethiopia

Basha Chekesa, Balako Gumi, Mahlet Chanyalew, Aboma Zewude, Gobena Ameni

2020-05-19 // PLOS ONE // Research Article

The yield of community-based tuberculosis and HIV among key populations in hotspot settings of Ethiopia: A cross-sectional implementation study

Z. G. Dememew, D. Jerene, D. G. Datiko, N. Hiruy, A. Tadesse, T. Moile, D. Bekele, G. Yismawu, K. Melkieneh, B. Reshu, P. G. Suarez

2020-05-29 // PLOS ONE // Research Article

COVID-19 diagnostics—not at the expense of other diseases

Priya Venkatesan