WHO and FIND: Technical guide on sequencing
The World Health Organization (WHO) and FIND released a technical guide on sequencing, The use of next-generation sequencing technologies for the detection of mutations associated with drug resistance in Mycobacterium tuberculosis complex: technical guide.
The guide summarizes the characteristics of available Mycobacterium tuberculosis (MTB) next-generation sequencing (NGS) technologies along with the current knowledge of the genetic basis of MTB drug resistance and presents guidelines for NGS technology selection, procurement and implementation by TB reference laboratories in low- and middle-income countries for the diagnosis of drug resistance in TB clinical samples.
Download the guide here.
