Items tagged with Scientific research

Russian clinical trials market in 2012-2017 (post)

The Association of Clinical Trials Organizations published its newsletter “Russian clinical trials market in 2012-2017”. Information about HCV, HIV and TB drugs is included.

Scientists break down TB structure (post)

Scientists from the University of British Columbia have taken a crucial step towards starving out tuberculosis, following research into how the infection grows in the body.

Research revealing ‘persistent bacteria’ could be key to future TB trials (post)

Research carried out by St George’s, University of London into tuberculosis treatments has clearly shown the ‘persistent bacteria’ that make treating the disease so difficult for the first time, using a new combination therapy.

Evidence of TB-like infection found in 245-million-year-old marine reptile (post)

A team of researchers from Poland and the U.S. has found possible evidence of tuberculosis in a 245-million-year-old marine reptile. In their paper published in the journal Royal Society Open Science, the group describes their study of the fossilized remains of a Proneusticosaurus silesiacus specimen and why they believe the creature had a TB-like disease.

Confronting TB resistance (post)

Tuberculosis, caused by Mycobacterium tuberculosis, is a highly infectious lung disease in humans.Unfortunately, resistance to anti-tubercular medicines such as fourth-generation fluoroquinolones is on the rise. In most cases, fluoroquinolone resistance is caused by mutations in a bacterial enzyme called gyrase.

New study observes tuberculosis bacteria attacking antibiotics (post)

Tuberculosis was one of the deadliest known diseases, until antibiotics were discovered and used to dramatically reduce its incidence throughout the world. Unfortunately, before the infectious disease could be eradicated, drug-resistant forms emerged as a major public health threat — one quarter of the world’s population is currently infected with TB and 600,000 people develop drug-resistant TB annually.

Sequencing studies show how TB moved with humans, adapted to treatments (post)

ATLANTA, Jun 12, 2018 – The bacterium that causes tuberculosis has an intertwined relationship with humans, according to new sequencing studies.

Scientists discover how vitamin A drives the lung immune system to control TB (post)

Scientists at Trinity College Dublin and St James’s Hospital, Dublin, have discovered how vitamin A drives the lung immune system to deal with tuberculosis (TB). The findings have just been published in a top respiratory journal, the American Journal of Respiratory Cell and Molecular Biology.

Blood signature could improve early TB diagnosis (post)

A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin. Such a signature has now been developed by a team led by the Francis Crick Institute and University of Leicester, in collaboration with BIOASTER and bioMérieux in France and the University of Cape Town in South Africa.

Repurposing promising cancer drugs may lead to a new approach to treating TB (post)

Promising experimental cancer chemotherapy drugs may help knock out another life-threatening disease: tuberculosis (TB). A new study published by scientists at Texas Biomedical Research Institute in San Antonio pinpoints a mechanism in regulating cell death called apoptosis that is a potential new target for helping to control the bacterial infection (Mycobacterium tuberculosis or M.tb) that causes the lung disease TB. 

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