Items tagged with Scientific research
In research that promises a new approach to treating an age-old human scourge, scientists have found a way to weaken the bacterium that causes tuberculosis and boost its vulnerability to drugs that are rapidly losing their power to cure.
DURHAM, N.C., 26-Apr-2018 -- Biomedical engineers have discovered an unlikely potential ally in the global fight against tuberculosis -- an FDA-approved drug originally designed to treat cancer.
Beyond killing TB (post)
Historically, our view of host defense against infection was that we must eliminate pathogens to eradicate disease. However, this perspective has recently been challenged as scientists have taken a lesson from plant biologists about an ancient strategy involving the ability to “tolerate” rather than “resist” infection to maintain health. This concept, referred to as “disease tolerance”, provides an opportunity to develop new strategies that mitigate the consequences of infection.
New research in mice suggests that chronic infection with intestinal worms indirectly reduces the number of cells in lymph nodes near the skin, inhibiting the immune system's response to the Bacille Calmette-Guerin (BCG) vaccine for tuberculosis. Xiaogang Feng of Karolinska Institutet in Stockholm, Sweden, and colleagues present these findings in PLOS Pathogens.
The mechanism our immune cells use to clear bacterial infections like tuberculosis (TB) might also be implicated in Parkinson's disease, according to a new collaborative study led by the Francis Crick Institute, Newcastle University and GSK.
LSTM's Dr Maxine Caws is co-lead investigator on an advanced genetics study published in Nature Genetics, which has shown that a virulent strain of tuberculosis (TB) has adapted to transmit among young adults in Ho Chi Minh City, Vietnam.
Antimicrobial resistance is on the rise worldwide. This is becoming a problem for infectious diseases like tuberculosis as there are only a few active substances available to combat such diseases. Pharmacists at Martin Luther University Halle-Wittenberg (MLU) have now found a way to increase the efficacy of a common tuberculosis agent while, at the same time, reducing resistance to it. The research group presents its latest developments in the international journal Molecules.
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