Items tagged with Scientific research
The number of drug-resistant tuberculosis (TB) cases is rising globally. But a newly discovered natural antibiotic — produced by bacteria from the lung infection in a cystic fibrosis patient — could help fight these infections. Lab testing reported in the Journal of the American Chemical Society shows that the compound is active against multi-drug resistant strains.
The battle against tuberculosis (TB) is closer to being won after University of Queensland students identified promising inhibitory compounds during a molecular microbiology practical course this semester.
Brian VanderVen, assistant professor of microbiology and immunology, and colleagues at Cornell’s College of Veterinary Medicine, have discovered a key metabolic mechanism in Mycobacterium tuberculosis(Mtb) bacteria, which presents as a novel drug target for potentially treating tuberculosis. The finding is published in the journal eLife.
26.06.17 - EPFL scientists show how some pathogenic bacteria — such as the mycobacteria that cause tuberculosis — use a previously unknown mechanism to coordinate their division. The discovery could help develop new ways to fight them.
A team of researchers at the University of Central Florida has discovered a potential new weapon in the fight against tuberculosis, and it lives in the Little Mermaid’s realm.
Antibiotic resistance is a growing problem, especially among a type of bacteria that are classified as “Gram-negative.” These bacteria have two cell membranes, making it more difficult for drugs to penetrate and kill the cells.
A group of Indian scientists have identified molecules that are effective in inhibiting the growth of tuberculosis-causing bacteria Mycobacterium tuberculosis. The molecules target an important gene, IdeR, which is essential for the survival of the bacteria. This development could lead to new drugs against TB in future.
New Rochelle, NY, July 21, 2017–Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin--a peptide involved in inflammation, immunity, and control of iron levels--is associated with greater susceptibility to extrapulmonary tuberculosis. Individuals with this single nucleotide polymorphism (SNP) make significantly less hepcidin in response to infection by Mycobacterium tuberculosis, as reported in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Genetic Testing and Molecular Biomarkers website until August 18, 2017.
Identification of novel antigen candidates for a TB vaccine in the adult zebrafish (Danio rerio) (post)
The Indian subsidiary of US healthcare giant Johnson & Johnson (NYSE: JNJ) announced a new partnership with the Institute of Microbial Technology (IMTECH), part of the Council of Scientific and Industrial Research (CSIR), to unlock the potential of Indian science and help accelerate the discovery of innovative new tuberculosis (TB) treatments.
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