Items tagged with Pediatrics

Johnson & Johnson announces new grant to Harvard Medical School to combat drug-resistant tuberculosis (post)

New collaboration will help address significant global unmet needs in pediatric drug-resistant tuberculosis (DR-TB) treatment and optimize use of existing DR-TB treatments

Death and disability: the outcomes of tuberculous meningitis (post)

The most feared consequence of infection with Mycobacterium tuberculosis in infants and young children is tuberculous meningitis. In the 1930s, researchers established that infants and young children are particularly susceptible to tuberculous meningitis, and that it is the major cause of tuberculosis-related childhood death (1, 2). The numbers of deaths due to tuberculous meningitis worldwide each year are unknown because of difficulties in diagnosis and under-reporting of tuberculosis in children, especially when infection causes early death. However, tuberculous meningitis is probably a major contributor to the estimated 200 or more child deaths every day due to tuberculosis worldwide (3). Furthermore, as other common causes of meningitis in infants and children become less common with the rollout of effective bacterial conjugate vaccines, M tuberculosis becomes relatively more important as a preventable and treatable pathogen causing death and disability due to bacterial meningitis in children (4—6).

Once weekly combination regimen effective for childhood tuberculosis (post)

MedicalResearch.com Interview with:
Dr. Stefan Goldberg MD
Medical Officer in CDC’s Division of Tuberculosis Elimination
Clinical Research Branch

Pharmacokinetics and safety of moxifloxacin in children (post)

Moxifloxacin concentrations were lower in children than adults according to pharmacokinetic (PK) data presented at the 45th Union World Conference on Lung Health. [1]

TB in the ARROW trial of children on ART (post)

Incidence of TB disease was highest in the first three months in children with HIV receiving antiretroviral treatment (ART) in the ARROW trial. [1]

Problems giving current second line TB drugs to children (post)

Results from a survey presented at 45th Union World Conference on Lung Health reveal an urgent need for child appropriate formulations of second line TB drugs. [1]

TB Alliance announces partnership with U.S. Fund for UNICEF to increase access to impending new child-friendly TB treatments (post)

TB Alliance has announced a new partnership with the U.S. Fund for UNICEF that will dramatically increase the scope and impact of child and maternal health programs around the world to include the diagnosis and treatment of pediatric tuberculosis (TB), a significant cause of child mortality.

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