Items tagged with Latent TB

Latent TB: a time bomb among people living with HIV in Kenya (post)

World TB Day (24 March) highlights the need to reach, treat and cure everyone who has the disease. So why are people living with HIV in Kenya, who could also have latent tuberculosis, not offered effective diagnostic tests which mean they can receive early treatment?

How the human immune system keeps TB at bay (post)

COLUMBUS, Ohio – A new tissue culture model using human white blood cells shows how people with a latent – or symptom-free – tuberculosis infection are protected from active disease by a critical early step in their immune response, researchers say.

Study: High incidence of latent TB infection among South African health workers (post)

Researchers from the Wits Reproductive and HIV Research Unit, Aurum Institute and others call for an urgent response to high levels of tuberculosis (TB) infection in South African Health workers.

Tuberculosis bacteria hide in the low oxygen niches of bone marrow stem cells (post)

A new study from the Forsyth Institute is helping to shed light on latent tuberculosis and the bacteria's ability to hide in stem cells. Some bone marrow stem cells reside in low oxygen (hypoxia) zones. These specialized zones are secured as immune cells and toxic chemicals cannot reach this zone. Hypoxia- activated cell signaling pathways may also protect the stem cells from dying or ageing. A new study led by Forsyth Scientist Dr. Bikul Das has found that Mycobacterium tuberculosis (Mtb) hijack this protective hypoxic zone to hide intracellular to a special stem cell type. The study was published online on June 8th in the American Journal of Pathology.

Canada: Tuberculosis study in Nunavut tests new treatment for latent TB (post)

An Ottawa researcher is studying a new treatment for latent tuberculosis which he hopes can help cure more patients before they show symptoms and the disease becomes contagious. 

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