Items tagged with Diagnostics
Cepheid, FIND & Rutgers announce collaboration for next-generation innovations to game-changing Xpert MTB/RIF test (post with simple image)
Xpert MTB/RIF Ultra, the next-generation test for Mycobacterium tuberculosis, will be with increased sensitivity to aid in detection of patients with smear-negative TB, which is often associated with HIV co-infection.
New WHO publication: Xpert MTB/RIF implementation manual (post with simple image)
Technical and operational ‘how-to’: practical considerations
The Union's SPARK-TB Plus program introduces Xpert MTB/RIF testing to the private sector in Uganda (post with simple image)
20 January 2015 - Uganda - The introduction and WHO endorsement of the Xpert MTB/RIF assay in 2010 revolutionized TB diagnosis. The assay's improved sensitivity and specificity compared with smear microscopy means it is able to confirm TB disease in smear negative patients. This provides a huge benefit to people living with HIV/AIDS who often test negative by smear microscopy. In addition, the Xpert MTB/RIF test reduces the time needed to diagnose resistance to rifampicin from six weeks to just two hours. In Uganda, the first GeneXpert system was placed in the National Referral Hospital in Mulago in 2011. Since then, the National TB and Leprosy Program (NTLP) has installed 59 systems countrywide.
Case study of Xpert MTB/Rif implementation in Brazil (post with simple image)
This case study documents the experience of a pilot study to implement Xpert®MTB/Rif to replace sputum smear microscopy to diagnose pulmonary tuberculosis in Brazil's Unified Health System in two municipalities.
Stop TB Partnership staff get tested for TB: A call for universal access to TB testing (post with simple image)
12 March 2015 -- Geneva, Switzerland -- In an initiative to highlight that there should be no stigma associated with tuberculosis (TB) and that anyone could be infected with TB no matter where they live, the Stop TB Partnership Secretariat staff, colleagues from UNOPS and the Global Fund to Fight AIDS, Tuberculosis & Malaria are today getting tested through an interferon gamma release assay (test) that will determine if the person is infected with latent TB.
Tuberculosis diagnostics in 2015: Landscape, priorities, needs, and prospects (post with simple image)
Special open access supplement to The Journal of Infectious Diseases on TB diagnostics.
MSF: Multidrug-resistant TB strain in Swaziland not detectable by most advanced rapid diagnostic tests (post with simple image)
It is essential to conduct studies that can determine whether this mutation is present in neighboring countries such as South Africa or Mozambique: “If we’re facing wide distribution of this strain in Southern Africa or elsewhere, it is imperative that the rapid molecular tests we currently use, as well as those under development, be adapted to detect a wider range of mutations”.
Madhukar Pai: Transforming the diagnosis of tuberculosis (post with simple image)
Interview with Professor Madhukar Pai, MD, PhD by Claire Raison
Advancing TB test technology, where it matters most (post with simple image)
On a recent morning in a Ho Chi Minh City intensive-care unit, Cao Thi My Hanh sat crying and clutching her 5-month-old granddaughter, Nguyen Dang Thanh Phuong. More than a month earlier she had noticed the baby coughing and struggling to breathe. Hanh took her granddaughter to see several doctors in her rural province, but they all failed to give her a proper diagnosis. When she finally reached this large urban hospital, she found out that Phuong had tuberculosis, and realized the weeks of inadequate care had given the life-threatening illness time to take hold.
HIV i-Base/TAG: 2015 Pipeline Report (post with simple image)
Latest annual review on HIV, HCV and TB drugs, diagnostics, vaccines, preventive technologies, research toward a cure, and immune-based and gene therapies in development.
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