Items tagged with Diagnostics
Latent TB detection: QuantiFERON-TB Gold Plus vs QuantiFERON-TB Gold In-Tube (post)
DALLAS — Positive results with respect to the presence of latent tuberculosis infection (LTBI) in patients with renal failure were more consistent with the use of QuantiFERON-TB Gold Plus (QFT-G plus) testing compared with the use of QuantiFERON-TB Gold In-Tube (QFT-GIT) testing.
TB treatment monitoring: Molecular bacterial load assay vs standard testing (post)
DALLAS — Compared with standard of care tests and most clinical signs, the molecular bacterial load assay demonstrated higher sensitivity and more rapid turnaround times for monitoring tuberculosis (TB) treatment, according to study results presented at the American Thoracic Society International Conference held May 17-22, in Dallas, Texas.
Xpert Ultra test for diagnosing TB now included in Cochrane Review (post)
Tuberculosis (TB) causes more deaths globally than any other infectious disease and is a top 10 cause of death worldwide. Globally in 2017, of the estimated 10 million people with TB, 3.6 million were not reported to national TB programmes, many of whom were not being diagnosed with their disease. When it is detected early and effectively treated, TB is largely curable, but in 2017, around 1.6 million people died of tuberculosis, including 300,000 people living with HIV.
New rapid test significantly more effective for TB diagnosis in people with HIV (post)
Compared to the only other approved device for TB detection in people living with HIV, the new FujiLAM point-of-care test offers superior diagnostic sensitivity.
Fourth generation QuantiFERON-TB Gold noninferior to previous in immunocompromised (post)
In patients who are immunocompromised, such as people living with HIV, the new fourth-generation QuantiFERON-TB Gold Plus (QFT-Plus) assay demonstrated similar sensitivity to the third-generation interferon-gamma release assay for the diagnosis of latent tuberculosis (TB), according to study results presented at American Society of Microbiology (ASM) Microbe 2019, held June 20 to 24 in San Francisco, California. In addition, researchers noted that increasing age was strongly correlated with positive results on the assay.
Earlier diagnosis and treatment assessment of TB achieved with PET/CT (post)
ANAHEIM, CA, June 24, 2019 – Research presented at the Society of Nuclear Medicine and Molecular Imaging’s 2019 Annual Meeting shows that molecular imaging with 18F-FDG positron emission tomography/computed tomography (PET/CT) can evaluate tuberculosis at the molecular level, effectively identifying diseased areas and guiding treatment for patients.
Researchers develop faster, cheaper test for TB (post)
Diagnosing tuberculosis might soon be cheaper and take less time thanks to a test developed by researchers at the Texas Biomedical Research Institute’s Population Health program.
Standard TB tests may not detect infection in certain exposed individuals (post)
CLEVELAND – An international collaboration of infectious disease experts has identified a large group of people who appear to have naturally mounted an immune response to TB, a bacterial infection that is the leading cause of infectious disease death worldwide. Nearly 200 people from 2500 households with active TB were clearly exposed to TB for more than 10 years but the two most reliable tests (TST and IGRA) came back negative on repeated tests.
Unitaid’s investment in TB hits record levels with new grant for diagnostic technologies (post)
Geneva – The Foundation for Innovative New Diagnostics (FIND) and Unitaid signed a US$ 14.5 million grant Thursday (July 4) to deploy a powerful new technology in the diagnosis of drug-resistant tuberculosis.
New blood test for human TB may also identify people most at risk (post)
A new study conducted by researchers in Leicester and Nottingham has shown the potential for a new blood test to not only diagnose human tuberculosis (TB) but also identify those at most risk of developing the disease, according to findings published in medical journal Clinical Infectious Diseases.
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