Brief news reports on Tuberculosis

New WHO guidelines call for more evidence on drug-resistant TB

The European Respiratory Journal is today (04 August 2011) publishing the updated guidelines of the World Health Organization (WHO) that aim to help manage drug-resistant tuberculosis (TB).

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An advance toward an “electronic nose” urine test for TB

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TB medicines are now part of the South African drug tender process

Health officials have negotiated 18% price cuts with suppliers of antibiotics and tuberculosis drugs, saving R242m over two years. [Read the story on Business Day.]( "State secures big savings on drug prices")

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UH Case Medical Center to commence Phase 1 clinical trial on TMC207

University Hospitals (UH) Case Medical Center will begin a Phase 1 clinical trial on a new experimental anti-tuberculosis drug called TMC207. This drug represents the first new class of anti-TB drugs in the past 60 years and it has activity against both drug-susceptible and drug-resistant TB.

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New TB drug-resistance test shows promise but needs investment for those diagnosed to be cured

Two research studies in this week's PLoS Medicine suggest that a new automated DNA test for tuberculosis (Xpert MTB/RIF), which can detect TB within 2 hours and has been endorsed by the World Health Organization, can significantly increase TB detection rate compared to other tests, particularly in HIV positive patients who have a high risk of being infected with TB, including multidrug resistant TB. An accompanying Essay and Perspective highlight the economic challenges and implications of such diagnostic tests.

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Urine test for TB marker not ready for routine use: review

The lipoarabinomannan (LAM) urinary assay isn't accurate enough to be used for routine diagnosis of active tuberculosis (TB), according to a review in the European Respiratory Journal.

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