News

Brief news reports on Tuberculosis

Research on TB tests prompts first-ever WHO negative policy

No policy has ever recommended serological (antibody) tests to detect active tuberculosis (TB) yet dozens of these blood tests are currently marketed and sold in developing countries where regulation is weak or non-existent. More than a million of these unapproved tests are carried out every year, usually at a high cost – financial and human – to unsuspecting patients. Mounting evidence clearly shows that the tests do not accurately diagnose TB – they often cause false-positives and false-negatives – and they are not as cost effective as other recommended TB tests.

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U.S. delegation in South Africa to renew bilateral relationship, create sustainable partnerships in health

This post on the Center for Strategic and International Studies (CSIS)'s Commission on Smart Global Health Policy blog examines tuberculosis (TB) in South Africa, "which has the highest tuberculosis infection rate per population and accounts for 5 percent of the global TB burden."

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Immune Network to start clinical trial of оral mycobacterium vaccae in tuberculosis patients

VANCOUVER, British Columbia, Aug. 10, 2011 (GLOBE NEWSWIRE) -- Immune Network Ltd. reports that its business partner Immunitor company has launched a Phase 2 clinical trial of a novel anti-tuberculosis immunotherapy consisting of orally-delivered, heat-inactivated Mycobacterium vaccae. The new tableted preparation was formulated according to clinically validated proprietary technology developed by Immunitor company.

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UNITAID seeking letters of intent to promote uptake of diagnostic technologies

Following a decision by its Board, UNITAID has issued a call for letters of intent on the topic of diagnostics for HIV, tuberculosis and malaria.

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Marker found for predisposition to tuberculosis

Scientists believe they have found a marker indicating genetic predisposition to tuberculosis, bringing closer the day when doctors can adjust therapies to individuals based on their genotype. Two mutations in an immune system gene called TLR1 are responsible for cellular changes that bring resistance to TB, according to research presented in the Journal of Leukocyte Biology.

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Few HIV patients tested for TB

Only 1 percent of HIV-positive patients worldwide have been tested for tuberculosis, a curable infection that frequently kills those living with AIDS.

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Towards lab-free tuberculosis diagnosis

Tuberculosis (TB), fuelled in part by the HIV epidemic, remains a major challenge to public health. Despite the potential for most cases of tuberculosis to be curable, TB causes around two million deaths per annum. These deaths are in part due to late or missed diagnosis. Improving the performance of diagnostics and their availability are key to reducing global morbidity and mortality.

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New WHO guidelines call for more evidence on drug-resistant TB

The European Respiratory Journal is today (04 August 2011) publishing the updated guidelines of the World Health Organization (WHO) that aim to help manage drug-resistant tuberculosis (TB).

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An advance toward an “electronic nose” urine test for TB

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TB medicines are now part of the South African drug tender process

Health officials have negotiated 18% price cuts with suppliers of antibiotics and tuberculosis drugs, saving R242m over two years. [Read the story on Business Day.](http://www.businessday.co.za/articles/Content.aspx?id=150055 "State secures big savings on drug prices")

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