Brief news reports on Tuberculosis

Researchers uncover why the body can't defend against TB

Tuberculosis, which kills over 2 million people each year, is caused primarily by infectious bacteria known as Mycobacterium tuberculosis – or Mtb. Mtb targets human immune cells as part of its strategy to avoid detection, effectively neutralizing the body's immune response.

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TB Alliance to advance testing of improved TB treatments

(Durban, SOUTH AFRICA,) The TB Alliance today announced the launch of a collaboration with the National Institute of Allergy and Infectious Diseases’ (NIAID) AIDS Clinical Trial Group (ACTG) to conduct and help complete a Phase III clinical trial testing potentially faster-acting tuberculosis (TB) treatments. Few clinical trials for TB have been conducted under modern GCP/GCLP standards in the past 40 years, and the infrastructure to support invigorated global TB drug research is lacking, especially in resource-limited settings where the majority of TB cases are found. The partnership between the NIAID’s ACTG and TB Alliance joins available resources with the urgent need for TB clinical research capacity to accelerate testing of new therapies that can benefit both the HIV/AIDS and TB communities.

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North Korea struggling to fight epidemic of drug-resistant TB

North Korea is grappling with a strain of the deadly lung disease tuberculosis that is resistant to conventional treatment. Humanitarian workers say the impoverished communist country, which already has one of the highest rates of tuberculosis outside of sub-Saharan Africa, is unable to cope with the outbreak.  Most victims could die of the disease within years. But some help is coming from an outside foundation.

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Poor adherence not enough to cause development of MDR-TB

Poor adherence may not be enough to cause multidrug-resistant tuberculosis, a laboratory study published in the online edition of the Journal of Infectious Diseases suggests.

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XPert MTB/RIF found to be cost effective in low- and middle-income settings

A study led by Frank Cobelens of the Amsterdam Institute of Global Health and Development, Amsterdam, The Netherlands and colleagues reports on the cost-effectiveness of implementing the Xpert MTB/RIF diagnostic test for tuberculosis (TB) in high burden countries. Based on their findings, which are published in this week's PLoS Medicine, the authors predict that Xpert will be a cost-effective method of TB diagnosis, compared with current standard techniques, in low- and middle-income countries.

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ECDC: 80,000 cases of TB infection a year in Europe

Europe's health is suffering, with around 80,000 cases of tuberculosis infection a year and serious problems with measles, HIV and threats from "superbug" infections, an annual health report on the region said Thursday.

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New agreement to speed development of TB drug combinations

• AstraZeneca, Bayer, Sanofi, Tibotec, TB Alliance, and the World Health Organization sign partnership to share information on TB drugs in development
• FDA’s Dr. Janet Woodcock keynotes CPTR Workshop and highlights the need for regulatory science to advance regimen development for life-threatening diseases.

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China works to tackle TB/HIV

The 17th Core Group Meeting of the TB/HIV Working Group kicked off in Beijing China with opening remarks from Dr. Yu Jingin, director of the Disease Control Bureau of the China Ministry of Health, and Dr. Wang You, director of the China Centers for Disease Control (CDC).

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Weakest link in war against TB: Community participation

Around one third of the world population is estimated to be infected with the TB bacterium and is at risk of developing the disease. There were 8.8 million new cases of TB in 2010 and the disease killed a staggering 1.4 million people.

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South Africa: 'I would rather have HIV than TB'

"Which disease would you rather have: HIV or TB? I would rather have HIV," Professor Francois Venter from the Wits Reproductive Health and HIV Institute told a stunned audience at the recent 42nd Union World Conference on Lung Health held in Lille, France.

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