News

Brief news reports on Tuberculosis

IAS 2017: XDR-TB emerges in 1990s in South Africa fueled by HIV

PARIS – Extensively drug-resistant tuberculosis (XDR-TB) emerged and was widely transmitted in South Africa long before it was spotted by public health surveillance efforts, and at least a decade earlier than the first reported outbreak in 2005, a presentation Monday (July 24) showed. The start of the spread was concurrent with the steep rise in both HIV and TB incidence in the early 1990s.

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Brochure on people-centered TB care

TB Europe Coalition releases a brochure highlighting the civil society position on quality people-centered TB care.

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European researchers identify a mechanism of protection of the new TB vaccine MTBVAC

Researchers at the University of Zaragoza (belonging to CIBERES) and the biopharmaceutical vaccine company Biofabri in Porrino, Spain in partnership with the TuBerculosis Vaccine Initiative (TBVI) are developing a new TB vaccine, MTBVAC. MTBVAC, a live attenuated M.tuberculosis vaccine, has been shown to provide improved protection as compared to BCG and the mechanism behind this greater efficacy has been hypothesized to be due to the ability of MTBVAC to present a wider collection of antigens of M. tuberculosis.

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Add antimicrobials to cut death risk in advanced HIV

For people with advanced HIV, enhanced antimicrobial prophylaxis significantly reduces the chance of death for any cause in the months after starting antiretroviral therapy, researchers reported.

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The world can’t afford to forget tuberculosis

The international community will need an expanded, cooperative, and holistic response to tuberculosis if it is to eliminate the ancient disease, James Trauer writes.

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MSF sounds alarm over high numbers of people dying with AIDS in sub-Saharan Africa

Global attention needed to prevent and treat AIDS in antiretroviral era, with 50% of hospital admissions in MSF hospitals already on treatment and showing clinical signs of failure; TB and cryptococcal meningitis remain HIV patients’ primary comorbidities.

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IJTLD August 2017 issue now online

The International Journal of Tuberculosis and Lung Disease (IJTLD) is the official publication of the International Union Against Tuberculosis and Lung Disease (The Union).

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A genetic variation may increase TB susceptibility

New Rochelle, NY, July 21, 2017–Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin--a peptide involved in inflammation, immunity, and control of iron levels--is associated with greater susceptibility to extrapulmonary tuberculosis. Individuals with this single nucleotide polymorphism (SNP) make significantly less hepcidin in response to infection by Mycobacterium tuberculosis, as reported in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Genetic Testing and Molecular Biomarkers website until August 18, 2017.

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Unitaid publishes its latest TB Diagnostic Technology Landscape

The Landscape presents a comprehensive overview of TB diagnostic technologies that are commercially available or close to market.

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Cost-effectiveness of isoniazid preventive therapy among HIV-infected patients clinicaly screened for latent TB infection in Dar es Salaam, Tanzania: A prospective cohort study

Abstract

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