Rabita Aziz

Integrating HIV treatment and TB preventive therapy greatly improves IPT adherence

THE HAGUE, Netherlands – When tuberculosis preventive therapy is delivered with HIV treatment services and patients get a choice in where they access treatment, completion of tuberculosis preventive therapy rises, helping to ensure people living with HIV stay healthy, researchers said here. This model of prevention should be scaled up in TB-HIV high burden settings, researchers said.

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90 percent of participants in short-course XDR-TB regimen cured after six months

THE HAGUE, Netherlands – New results from the ongoing Nix-TB trial continue to confirm a short-course treatment regimen of bedaquiline – one of the two newest drugs to treat TB in half a century – linezolid and pretomanid offers a significantly improved treatment option for people infected with drug resistant forms of tuberculosis, researchers said here.

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Private provider engagement led to 10-fold increase in Mumbai TB case detection

THE HAGUE, Netherlands, October 26 – In Mumbai, the largest city in the world’s highest TB burden country, more than half of people living with active tuberculosis disease go undetected and undiagnosed every year. Much of the failure to adequately detect TB cases stems from a dependence on the private sector for health care – more than 70 percent of Mumbai’s TB patients seek care in the private sector. It is a sector that is plagued by suboptimal quality issues, Lal Sadasivan with PATH said here today.

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Study shows scaling up TB prevention in children is possible

THE HAGUE, Netherlands, October 25, 2018 – Children – especially very young children – are at high risk of developing severe tuberculosis illness when exposed to a member of their household who has active disease, but only 23 percent of child contacts of adults with active disease are provided with TB preventive therapy, researchers said here. That leaves 1.3 million children under the age of five who are eligible for isoniazid preventive therapy without access to the intervention that would prevent illness, according to the World Health Organization. Preliminary results from a study released here show how that can change.

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GeneXpert can test stool samples to accurately diagnose TB in children

THE HAGUE, Netherlands, October 25, 2018 – Drug susceptible and drug resistant forms of tuberculosis in children can be accurately diagnosed by using existing GeneXpert machines and cartridges to test stool samples for TB bacteria, researchers announced here. Not only can GeneXpert accurately diagnose TB and drug resistance in a fraction of the time it takes to diagnose TB using sputum, Petra de Haas of the KNCV Tuberculosis Foundation said, in a study conducted in Indonesia comparing the two samples more TB cases were detected using stool samples than sputum samples.

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First promising TB vaccine candidate in 100 years needs more resources, researchers say

THE HAGUE, Netherlands, October 25, 2018 – When the Ebola outbreak hit West Africa in 2014 and took more than 11,000 lives in two years, public and private organizations mobilized the development of a vaccine in a year and a half. That vaccine now is being used to control the current outbreak in the Democratic Republic of Congo.

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TB advocates demand accelerated global response

First-ever Interactive Civil Society Hearing to prepare the UN High-Level Meeting on TB took place on 4 June 2018 at the UN Headquarters in New York.

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The link between TB, migration, human rights and ethics

Oliver is a 27 year old male who decides to migrate to Europe after experiencing violence, conflict and uncertainty in his home country in sub-Saharan African. It takes him two months to travel to a North African country where he lives in a warehouse with 25 other migrants seeking to earn enough money to pay smugglers to get them across the Mediterranean to southern Europe. There, on top of experiencing food insecurity and poor sanitation, Oliver develops a persistent cough and loses weight, which he attributes to his arduous journey and difficulties since then. He finally saves enough money to make the treacherous trip across the Mediterranean.

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Global burden of disease report shows gains made from HIV response, work that remains to respond to infectious disease

Global life expectancy has increased by 10.2 years since 1980, with the most marked increases occurring over the past decade in Sub-Saharan Africa, where the expansion of antiretroviral therapy and prevention of mother-to-child transmission of HIV activities have expanded life expectancy by more than ten years in countries with the highest HIV burdens.

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With TB now No.1 global infectious disease killer, USAID justifies cuts to global TB funding

When House Appropriations Committee members in 2014 asked then USAID Administrator Raj Shah how the U.S. could combat tuberculosis globally with 19 percent less money, he said not to worry. The Global Fund to Fight AIDS, TB and Malaria, and the President’s Emergency Plan for AIDS Relief would fill the gap, he said.

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