All-cause mortality was found to be higher in men vs women after treatment for tuberculosis (TB), according to results from a retrospective cohort study and a meta-analysis published in Clinical Infectious Diseases.

Despite having a good specificity for tuberculous pleural effusion diagnosis, genotype MTBDRplus line probe assay (MTBDRplus) could not be included in most diagnostic algorithms as a result of its low sensitivity, according to study results published in Infectious Diseases.

Immune reconstitution inflammatory syndrome (IRIS) occurs commonly in infants and young children with HIV who are initiating antiretroviral therapy (ART) in countries with a high prevalence of HIV and tuberculosis (TB), according to study results published in PLoS One.

The majority of cases of type 2 diabetes mellitus (DM) in patients with tuberculosis (TB) are diagnosed, but are poorly controlled in 4 TB-endemic countries, according to a study published in Clinical Infectious Diseases.¹ Moreover, many people with comorbid TB and DM had significant cardiovascular disease risk and severe TB.

In a brief report published in Clinical Infectious Diseases, researchers reported a case of drug resistance against 2 recently approved antitubercular medications: delamanid and bedaquiline. Researchers presented a patient with extensively drug-resistant tuberculosis (TB), and highlighted the potential for the emergence and transmission of resistant Mycobacterium tuberculosis complex strains with more frequent use of these relatively new drugs.

Chronic pulmonary aspergillosis complicates treated pulmonary tuberculosis (TB) frequently enough to represent an unrecognized global public health issue, according to a study published in the European Respiratory Journal.