Pulmonology Advisor

Effect of vitamin D supplementation on sputum culture conversion in TB

As a whole, vitamin D supplementation did not affect sputum culture conversion in patients with pulmonary tuberculosis (TB), but in the subgroup of patients with multidrug-resistant TB, vitamin D supplementation did accelerate sputum culture conversion, according to a meta-analysis published in European Respiratory Journal.

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Multidrug-resistant TB outcomes with pyrazinamide susceptibility testing

Introducing pyrazinamide molecular susceptibility testing in the treatment of multidrug-resistant tuberculosis improved outcomes without the use of new drugs and shortened the World Health Organization (WHO) 20+ month regimen to 12 months, according to a study published in the European Respiratory Journal.

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Elevated TB risk in inhaled corticosteroid users

The risk of contracting tuberculosis (TB) is greater in patients who use inhaled corticosteroids (ICSs) or who have used them in the past 3 years, and the risk is even greater in patients with chronic obstructive pulmonary disease (COPD), according to a study published in The Journal of Allergy and Clinical Immunology: In Practice

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